Testimonials from professional colleagues and clients who have used Consulting Services
"Malcolm's
work at Panasonic Boston Lab enabled us to evaluate the application of
our robot technology to the biotech industry. Malcolm's depth of
knowledge in biotech combined with an incredible insight to other
fields enabled him to provide us with superlative recommendations for
our business development in this growing field."
Dan Hogan, President at Panasonic Home & Environment Co.
"I
worked with Malcolm on a project related to development of a novel DNA
purification technology. Malcolm is well connected in the industry, has
deep knowledge, and great enthusiasm for science and technology."
Robert Hess Patent Agent at Bromberg & Sunstein, LLP. Boston, MA
"Malcolm
consulted for us on a project involving potential applications of our
company’s technology to proteomics. He was able to educate us on the
key aspects of relevant protein biochemistry, lead brainstorming
sessions, and develop concepts for potential products in sufficient
detail for us to market them to potential strategic partners. And he
did this in a remarkably time efficient way, and was a pleasure to work
with. I would engage Malcolm again with no hesitation.
Paul Pyzowski, President at Network Biosystems, Woburn, MA
"Malcolm
is a goal oriented, passionate, and very efficient individual that not
only does the work right, on time and under budget, but takes the time
to ensure his work is understood and well communicated to the right
people. I would hire Malcolm again at the first opportunity.
Roberto Rodriguez-Andujar, BioSciences Consultant at Puerto Rico Industrial Development Company
Recent Consulting Projects
- Application of lab and industrial automation technologies in DNA sample preparation and sequencing applications in a large genome sequencing center.
- Development of a large scale automation platform for compound storage and retrieval in a Pharmaceutical Drug discovery group.
- Development of a microfluidic platform for isolation of DNA from whole blood, on-board PCR and interface with fluorescent detection.
- Development of a microfluidic platform for chromatographic resolution of complex protein mixtures and interfacing with MS for Biomarker discovery.
- Troubleshooting a very large scale (>100 L culture)plasmid DNA purification process and the assembly of a unique cross-linked dendrimer nucleic acid detection reagent for microarrray applications.
- Technical market development for a large Lab Bioscience tools provider in the areas of Proteomic sample preparation technology linked to MALDI mass spectrometry.
- Technical due diligence of strategic IP in the Protein Microarray area to support a business licensing and acquisition negotiation. Involving IP technology value assessment and market value.
- Technical due diligence for a venture capital fund on a new fluorescence detection technology based on Quantum MicroDots.
- Product development support to a technology provider on anovel magnetic particle based sample preparation platform.
- Investigate chemical activation of glass supports for creation of a suitable substrate for protein microarray applications.
- Adapt protein spotting and array processing hardware for a major instrument provider to be able create and process protein microarrays on existing nucleic acid instrumentation.
- Development nof a unique manufacturing process for immobilized pH gradient (IPG)and second dimension SDS-PAGE gels for applications in two dimensional gel electrophoresis.
- Create unique intellectual property (patent pending) for a client in the area of membrane based preparative isoelectric focusing applications in Proteomic or Biomarker discovery pre-fractionation.
- Lead a team during Product development of a series of kits for sample preparation in Proteomics, including in-gel protease digestion (manual and automated platform) and abundant protein depletion.
- Created a detailed IP technology landscape to support the development of new technology in the cardiovascular and pathogen detection areas of Molecular diagnostics (MDx).
- Evaluated a new drug discovery platform based on affinity ligands utilizing 2DE analysis and ID of target proteins by ini-gel protease digestion and MALDI-MS analysis.
- Supported a large Lab Bioscience tools provider in the generation of a pipeline of new product ideas and application data in Proteomic sample preparation markets.
- Expert witness for a legal team involved in patent infringement litigation in an electrophoresis application area.
- Expert witness to a Lab Bioscience company legal team in a patent portfolio review as part of due diligence activity in a M&A process.
- Created a very comprehensive product protocol manual to support a Lab Bioscience product portfolio in market.
- Reduced to practice a novel solid phase chemistry for DNA and peptide synthesis on a unique substrate for creation of arrays of binding ligands.
- Produced a series of training lecture courses covering basic and advanced levels in Proteomics, electrophoresis and microarray technology. These lecture were given to large (>500) and small in-house groups and at workshops at international meetings.
- Organized "hands-on" training courses in Proteomics technologies as used in Biomarker discovery.
- Conducted an on-going training program to support cGMP production of protein biologic's in a large CMO setting
- Development of a novel (patents applied for) Western blotting technology for protein analysis and biomarker discovery.